Онкология EFFECTIVENESS EVALUATION RADIOGRAPHICALLY AND ENDOSCOPIC TUMOR RESPONSE ON NEOADJUVANT THERAPY IN PATIENTS WITH ESOPHAGEAL CANCER
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ONCOLOGY BULLETIN OF THE VOLGA REGION

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EFFECTIVENESS EVALUATION RADIOGRAPHICALLY AND ENDOSCOPIC TUMOR RESPONSE ON NEOADJUVANT THERAPY IN PATIENTS WITH ESOPHAGEAL CANCER

УДК 616.329-006.04-08-07

M.V. Aglullina1,2, N.A. Khasanova1,2, M.V. Burmistrov1-3, A.F. Khasanov1,2

1Tatarstan Саnсеr Center, Kazan

2Volga Region branch of N.N. Blokhin Russian Cancer Research Center, Kazan

3Kazan State Medical Academy, Kazan

Khasanova N.A. — Cand. Med. Sc., radiotherapist of radiology department №1 of the Tatarstan Саnсеr Center

29 Sibirskiy Trakt, Kazan, Russian Federation, 420029, tel.: (843) 519-21-12, +7-906-112-95-43, e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.

 

Abstract. The use of neoadjuvant therapy followed by esophagectomy improves long-term results of treatment of patients with locally advanced esophageal cancer, but the results of several randomized trials have shown that the survival benefits are only patients with significant pathologic response to neoadjuvant therapy. Assessment of tumor response is an important criterion in determining the effectiveness of chemo-radiotherapy planning and correction stages of treatment, the continuation of the feasibility of operation if chemo-radiation therapy and prognosis of the disease in patients with esophageal cancer. X-ray method is not conclusive in the assessment of tumor response to treatment. Endoscopic study after 2-4 weeks is more informative and therefore should be compulsory on a par with PET/CT for assessment of tumor response after chemo-radiotherapy.

Кеу words: esophageal cancer, neoadjuvant therapy, tumor response. 





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