Онкология EXPERIEVCE OF USING INTRACAVITY RADIATION THERAPY IN THE TREATMENT OF LOW-AMPULLARY CANCER OF THE RECTUM
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ONCOLOGY BULLETIN OF THE VOLGA REGION

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EXPERIEVCE OF USING INTRACAVITY RADIATION THERAPY IN THE TREATMENT OF LOW-AMPULLARY CANCER OF THE RECTUM

S.G. Afanasyev, A.S. Tarasova, Zh.А. Startseva

FSBE «Cancer Research Institute» of the SB of the RAMS, Tomsk

 

Abstract. The aim of the study was to evaluate efficacy of preoperative treatment with capecitabine in combination with radiation therapy in patients with stage II-III rectal cancer. Twelve patients were treated with capecitabine at a daily dose of 1650 мg/м2 and concomitant external beam radiation therapy followed by intracavitary radiation therapy. Short-term treatment results allow us to consider the devised program as effective and safe treatment method. The rate of complete response was 58.3%. Most of the patients underwent radical sphincter-preserving surgery. No disease progression was observed for long-term follow-up. Key words: rectal cancer, preoperative radiation therapy, intracavitary radiation therapy, radiosesitizer.

 





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